Delayed Wound Healing by the Absence of Cell Adhesion Molecules : Effect of cell Growth Factors

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  • Sato Shinichi
    Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences

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Other Title
  • 細胞接着分子欠損による創傷治癒遅延 : 細胞増殖因子の効果について

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During the wound healing process, inflammatory cell infiltration induces inflammatory process and promotes the wound healing by producing various growth factors and proinflammatory cytokines. This inflammatory cell infiltration is the process that is highly regulated by multiple cell adhesion molecule expression. Consistent with this notion, the would healing is delayed in mice lacking cell adhesion molecules. This delayed would healing by the absence of cell adhesion molecules is normalized by treatment with basic fibroblast growth factor. This indicates that basic fibroblast growth factor plays an important and critical role in the wound healing process.

Journal

  • Hifu no kagaku

    Hifu no kagaku 5 (Suppl.6), A40-A45, 2006

    Meeting of Osaka Dermatological Association/Meeting of Keiji Dermatological Association

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