The Anthelmintic Efficacy of Benzimidazoles and Ivermectin against <i>Strongyloides stercoralis</i> in Dogs

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  • ベンズイミダゾールとイベルメクチンの犬寄生<i>Strongyloides stercoralis</i> に対する駆虫効果

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The anthelmintic efficacy of benzimidazoles (parbendazole, thiabendazole, and albendazole) and ivermectin were evaluated in this study. They were given orally to eight dogs with Strongyloides stercoralis as the only parasite. When one medicine turned out to be ineffective in one dog, a second medicine was tried in the same dog. Eventually the number of dogs reached fourteen. First, parbendazole was given to two dogs at 30 mg/kg body weight once a day for 3 days, but showed no efficacy agaisnt Strongyloides stercoralis. Thiabendazole, which was given to five dogs at 75 mg/kg B.W. once a day for 3 days, was effective in three dogs (60% extermination). Albendazole, which was given to five dogs at 25 mg/kg B.W. twice a day for two days, showed 60% efficacy. Ivermectin, which was given to two dogs at 200 μg/kg B.W. one time, showed 100% efficacy.

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