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Three Cases of Immediate Hypersensitivity to Quinolones: Analysis of Cross-reactivity between Quinolones
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- JIMBO Haruki
- Department of Dermatology, Kobe University Hospital
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- FURUMATSU Akane
- Department of Dermatology, Kobe University Hospital
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- FUKUNAGA Atsushi
- Department of Dermatology, Kobe University Hospital
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- SHIMIZU Hideki
- Department of Dermatology, Kobe University Hospital
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- NISHIGORI Chikako
- Department of Dermatology, Kobe University Hospital
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- YAMASHITA Junji
- Division of Dermatology, Kobe Rosai Hospital
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- SARAYAMA Yasuko
- Division of Dermatology, Kobe Rosai Hospital
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- HARADA Susumu
- Harada Skin Clinic
Bibliographic Information
- Other Title
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- ニューキノロン系抗菌剤による即時型アレルギーの3例
- ―交差反応についての検討―
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Description
We report three cases of immediate hypersensitivity to quinolones. We divided quinolones into two groups: those consisting of a bicyclic or a tricyclic ring structure. The sensitizing and cross-reactivity drugs were as follows: ciprofloxacin and moxifloxacin with a bicyclic ring structure (Case 1), levofloxacin and pazufloxacin with a tricyclic ring structure (Case 2), and levofloxacin and ofloxacin containing its optical isomer (Case 3). It is likely that antigenic determinants are a cyclopropyl group in position 1 of a bicyclic ring structure and a pyridobenzoxazine ring of a tricyclic ring structure. Our data indicate that cross-reactivity of quinolones tends to occur within groups and may not occur between different groups.Skin Research, 13: 278-284, 2014
Journal
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- Hifu no kagaku
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Hifu no kagaku 13 (4), 278-284, 2014
Meeting of Osaka Dermatological Association/Meeting of Keiji Dermatological Association
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Details 詳細情報について
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- CRID
- 1390282680166852352
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- NII Article ID
- 130004706614
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- ISSN
- 18839614
- 13471813
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed