A Case of Lupus Vulgaris: Detection of Mycobacterium tuberculosis in Culture from a Biopsied Specimen

DOI
  • KATO Maiko
    Department of Dermatology, Kinki University Faculty of Medicine
  • MIYAKE Muneharu
    Department of Dermatology, Kinki University Faculty of Medicine
  • OISO Naoki
    Department of Dermatology, Kinki University Faculty of Medicine
  • KAWADA Akira
    Department of Dermatology, Kinki University Faculty of Medicine
  • TSUYUGUCHI Kazunari
    National Hospital Organization Kinki-Chuo Chest Medical Center

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Other Title
  • 尋常性狼瘡の1例

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Abstract

An 82-year-old woman was referred to us because of a slightly pruritic eruption on the right cheek. It had gradually enlarged in size over several years. Physical examination revealed a slightly pruritic, scaly erythematous plaque, 6×4cm in size, on the right cheek. A histopathologic specimen showed granuloma with central infiltration of epithelioid cells and Langhans giant cells and peripheral infiltration of lymphocytes without caseous necrosis in the upper and lower dermis. QuantiFERON TB Gold showed a positive reaction. We suspected that the eruption was lupus vulgaris, but acid-fast bacilli were not detected by Ziehl-Neelsen staining in a biopsied specimen and Mycobacterium tuberculosis DNA was not identified by polymerase chain reaction. However, Mycobacterium tuberculosis grew in a culture from a biopsied specimen on Ogawa egg medium three weeks later. Thus, we diagnosed the eruption as lupus vulgaris. Our case reemphasizes the importance of the detection of Mycobacterium tuberculosis by various methods of examination when we clinically and histopathologically suspect an eruption to be lupus vulgaris.Skin Research, 13: 172-175, 2014

Journal

  • Hifu no kagaku

    Hifu no kagaku 13 (3), 172-175, 2014

    Meeting of Osaka Dermatological Association/Meeting of Keiji Dermatological Association

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