A Canine Case of Malignant Trichoepithelioma with Bone Metastasis

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  • 骨転移をきたした悪性毛包上皮腫の犬の1例

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A 13 year-old female beagle was admitted with recurrent tumors in the skin extending from the third right cranial nipple to the left medial femoral region. Although The tumors, which had been present for 4 years, and were resected twice, however recurrence occurred. An initial histopathological diagnosis was invasive trichoepithelioma. Wide restriction was performed at our university hospital and our revised histopathological diagnosis was malignant trichoepithelioma. On the 56th day of illness (7 weeks after surgery), recurrence occurred again in the skin around the inguinal region. On the 127th day of illness (17 weeks after surgery), painful bone metastases to the lumbosacral to the caudal vertebrae were confirmed. From the 133rd day of illness, palliative radiotherapy for the bone metastases was performed to improve pain and quality of life. From the 148th day of illness, bisphosphonates (zoledronic acid) were administered to inhibit bone resorption and alleviate pain. Although the dog died at home on the 394th day of illness, pain had not increased and the dog was able to walk with good quality of life for the remainder of its life.

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