Change of Water Concentration in the Uterus of the Rat Following Relaxin Treatment

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  • WADA Hiroshi
    Department of Animal Husbandry, Faculty of Agriculture, Okayama University
  • YUHARA Masataka
    Department of Animal Husbandry, Faculty of Agriculture, Okayama University

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  • リラキシン注射後のラツテ子宮の水分量の変化
  • リラキシン チュウシャ ゴ ノ ラッテ シキュウ ノ スイブンリョウ ノ ヘンカ エイブン

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Abstract

Experiments were performed to investigate changes in water content of the uterine tissue in estrogen-primed, spayed mature rats following injection of a single dose of relaxin. Uterine water content increased rapidly. The hydration of the uterus reached its maximum 6 hours and then decreased gradually to its initial level about one day following a single subcutaneous injection of 30 guinea pig units of relaxin in water. Relaxin alone, however, had not any effect on uterine water content. Thus, relaxin increased uterine water content synergistically with estrogen. The nature of relaxin was also discussed.

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