マウス乳腺の核酸とくにリボ核酸量におよぼす選抜近交の効果

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  • 宋 永義
    東京大学農学部 Department of Animal Husbandry, National Taiwan University, Roosevelt Rd

書誌事項

タイトル別名
  • The effect of selection and inbreeding on the ribonucleic acid content of mammary gland in mice
  • マウス ニュウセン ノ カクサン トクニ リボ カクサンリョウ ニ オヨボス センバツ キンコウ ノ コウカ 2 ニュウセン ノ RNA DNAヒ ノ センバツ ノ コウカ エイブン
  • II. Effect of selection and inbreeding on the RNA/DNA ratio
  • II. 乳腺のRNA/DNA比の選抜の効果

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抄録

The effect of selection and inbreeding on the RNA/DNA ratio of mammary gland was studied. Adopting outbred CFW strain mice as a foundation stock, selection and full-sib mating were carried out until 13 th generation. The results are briefly summarized as follows.<br>1) Changes of fresh and D. F. F. weights of mammary gland, total DNA and RNA contents. and RNA/DNA ratio were seemed to increase slightly with generations but linear regressions on changes of these characters were not significant except the total RNA content. However, most of these changes were significant in cosideration with the control group to eliminate the effect of inbreeding depression.<br>The heritability of RNA/DNA ratio of mammary gland was computed by applying the ratio of response to selection. It was estimated as 2=+0.0998 and it seemed difficult to obtain easy validity of selection owing to the larger effect of environment on them.<br>2) The decrease of litter size by succession of selection and inbreeding was not clear in. this experiment. It seemed probable that selection on mammary function had indirect influence on the increase of the fertility.<br>Changes of various characters in mother with generations were estimated and discussed. All of these changes seemed to decrease with generations, but they were not significant except the second parturition weight, however, almost all of the regression coefficients of these characters. turn to positive if they are corrected by those of the cotrol group. But they also lack significance.<br>3) Change of body weight of pups showed a tendency to decrease with generations but they lacked significance. This seems to indicate that improving the mammary function may be avoided more or less the decrease of litter weight which was affected by inbreeding depression.<br>4) It was clear that the character of mammary function was more complicated than body weight character in comparison with those of coefficients of variation.

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  • 日本畜産学会報

    日本畜産学会報 41 (4), 197-208, 1970

    公益社団法人 日本畜産学会

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