Association Analysis between the Deletion Mutant Allele of Claudin-16 Deficiency and Carcass Traits in Japanese Black Cattle

DOI Web Site 4 Citations 22 References

Bibliographic Information

Other Title
  • 黒毛和種におけるウシClaudin-16 (CL-16) 欠損症遺伝子型と産肉成績との間のアソシエーション解析
  • クロゲワシュ ニ オケル ウシ Claudin 16 CL 16 ケッソンショウ イデンシガタ ト サンニク セイセキ ト ノ アイダ ノ アソシエーション カイセキ

Search this article

Description

Claudin-16 (CL-16) deficiency is an autosomal recessive disease in Japanese black cattle. The association analysis between the deletion mutant allele (d) of CL-16 deficiency and carcass traits was investigated. Normal allele (D) and mutant allele (d) were diagnosed in 464 fattened progeny of three carrier sires (Dd), and 140 cows of Sire 1 whose common ancestor was revealed as Dd. The progeny were composed of 230 normal (DD) and 234 carrier (Dd). The cows were composed of 60 DD and 80 Dd. The association analysis was carried out among the CL-16 genotypes, and carcass traits and predicted breeding value for carcass traits using the 464 progeny and 140 cows, respectively. Analysis of variance was performed considering the CL-16 genotypes, sire, sex, farm and age (linear and quadratic) as the source of variance in order to evaluate factors affecting carcass traits. Significant differences in BMS number, carcass weight, area of rib eye, and rib thickness were observed between the sires. Significant differences in carcass weight were observed in the influence of sex. Significant differences in BMS number, carcass weight, and rib thickness were observed between farms. The regression of any carcass traits on final age (linear and quadratic) was not statistically significant. The significant association of the CL-16 genotypes were not seen in the carcass traits after the effects of environmental factors were eliminated. Moreover, a significant association of the genotypes was not seen (P>0.05) with predicted breeding value for carcass traits in cows of Sire-1. Furthermore, these carcass traits had no significant linkage with the approximately 30 cM region including CL-16 locus in a half-sib family of Sire-1 comprising 136 offspring (P>0.05). Therefore, exclusion of the mutant allele d from Japanese Black cattle population would not deteriorate the carcass traits.

Journal

Citations (4)*help

See more

References(22)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top