雛における大豆トリプシン•インヒビター(SBTI)の栄養阻害作用に関する研究

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タイトル別名
  • The Influences of Soybean Trypsin Inhibitors on the Growth, Pancreatic Changes and Digestibility of Diet in Chicks
  • ヒナ ニ オケル ダイズ トリプシン インヒビター SBTI ノ エイヨウ ソガイ サヨウ ニ カンスル ケンキュウ

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Several experiments were conducted to study the effects of soybean trypsin inhibitors isolated from raw soybean meal on growth, pancreatic changes, fat absorption, metabolizable energy value and protein digestibility, and further, to determine whether these criteria were affected by added trypsin inhibitors. A crude trypsin inhibitor was prepared from raw soybean meal by modification of the method described by BOWMAN. The KUNITZ inhibitor and 1.9S inhibitor were prepared by the modification of the method described by YAMAMOTO and IKENAKA. These preparations were fed to chicks in experiments which was designed to study relative effects of feeding different trypsin inhibitors from raw soybean meal. The trypsin inhibitors were added to the control diet at levels to provide an amount of activity equivalent to a diet containing 41.3% raw soybean meal. Trypsin inhibitors depressed growth, caused pancreatic hypertrophy and decreased metabolizable energy value of the diet. The results of the experiment with KUNITZ, BOWMAN and 1.9S inhibitors suggested that they acted to cause the similar effects observed on raw soybean meal.<br>Pancreatic hypertrophy appears to occur in response to the trypsin inhibitor probably because of increased enzyme production to overcome the inhibitors.<br>The mechanism of the chick growth retardation could be explained by lowered digestibility of protein and lowered metabolizable energy value of the diet.<br>The possible significance of many contradictory results on the mechanism of growth inhibition by raw soybean meal was discussed in detail.

収録刊行物

  • 日本畜産学会報

    日本畜産学会報 38 (10), 435-442, 1967

    公益社団法人 日本畜産学会

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