-
- Takahashi Masateru
- Laboratory of Silkworm Science, Kyushu University Graduate School of Bioresource and Bioenvironmental Sciences
-
- Man Lee Jae
- Laboratory of Silkworm Science, Kyushu University Graduate School of Bioresource and Bioenvironmental Sciences
-
- Mon Hiroaki
- Laboratory of Silkworm Science, Kyushu University Graduate School of Bioresource and Bioenvironmental Sciences
-
- Kawaguchi Yutaka
- Laboratory of Silkworm Science, Kyushu University Graduate School of Bioresource and Bioenvironmental Sciences
-
- Koga Katsumi
- Laboratory of Silkworm Science, Kyushu University Graduate School of Bioresource and Bioenvironmental Sciences
-
- Kusakabe Takahiro
- Laboratory of Silkworm Science, Kyushu University Graduate School of Bioresource and Bioenvironmental Sciences
この論文をさがす
抄録
The silkworm, Bombyx mori, is known to be more resistant to ionizing radiation (IR) compared with mammals, but detailed processes underlying this resistance have remained largely unexplored. In this study, we have confirmed that silkworm larvae survived and showed no effect in the apparent reproduction ability after the irradiation of high doses of γ-ray. We have then observed the effects of γ-irradiation to cells of the silkworm cell line BmN4, which showed marked cell-cycle arrest at the G2/M phase, but not at the G1 or S phases. These cells did not undergo apoptosis after γ-ray irradiation in contrast to the mammalian cells wherein G1 arrests after IR causes apoptosis. After UV-C radiation to cells of BmN4 and Sf21 (a Spodoptera frugiperuda cell line), S-phase checkpoint activation was provoked. But there was also no observation of cell death in BmN4 cells, in contrast to Sf21 cells. Based on these results, we proposed that the extraordinary tolerance of induced DNA injury or the elimination of cell death programs after irradiation is a possible cause of the irradiation resistance in the silkworm cells.<br>
収録刊行物
-
- Journal of Insect Biotechnology and Sericology
-
Journal of Insect Biotechnology and Sericology 75 (1), 23-30, 2006
社団法人 日本蚕糸学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390282680172123520
-
- NII論文ID
- 130004464106
- 10017316146
-
- NII書誌ID
- AA11558849
-
- ISSN
- 18847978
- 13468073
-
- NDL書誌ID
- 7845814
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可