書誌事項
- タイトル別名
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- Effect of a Probiotic on Immune Responses in Broiler Chicks under Different Sanitary Conditions or Immune Activation
- Effect of a Probiotic on Immune Respons
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説明
The experiment was conducted to investigate the effects of immunostimulation and a probiotic (Bacillus cereus CIP 5832) on immune responses in broiler chickens. Two levels of B. cereus were given tomale chicks; either 0 or 50mg/kg (5×108cfu/kg) during the experimental periods. Chicks were kept at either a dirty or clean environment from one to 22 day of age and thereafter injected intraperitoneally with Escherichia coli lipopolysaccharide (LPS, 500μg/chick) as an immunostimulator 16 hours before the end of the experiment. A dirty environmental condition was achieved by raising multiple cycle of chicks in the batteries, cages, rooms, and by letting droppings, dust and dander accumulation before the start of the experiment. Dirty environmental condition reduced body weight gain and feed intake. Feeding B. cereus improved feed efficiency in chicks raised in the dirty environment, but not the body weight gain and feed intake. The proliferative response of mononuclear cells of spleen obtained from chicks kept at a dirty environment was lower than that from chicks kept at a clean environment. Feeding B. cereus prevented the reduction in the response in chicks raised in a dirty environment. A dirty environmental condition tended to increase the plasma IL-1 like activity in the saline-injected groups, and significantly enhanced the activity in the LPS-injected groups. Dietary B. cereus lowered the increased plasma IL-1 like activity following LPS injection in the chicks kept at dirty environment. The results suggested that sanitary condition affected immune responses, and LPS injection increased the changes in immune responses. Feeding B. cereus CIP 5832 could improve the changes induced by the immunostimulators.
収録刊行物
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- 日本畜産学会報
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日本畜産学会報 68 (6), 537-544, 1997
公益社団法人 日本畜産学会
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詳細情報 詳細情報について
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- CRID
- 1390282680172462080
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- NII論文ID
- 10024586722
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- NII書誌ID
- AN00195188
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- ISSN
- 18808255
- 00215309
- 1346907X
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- NDL書誌ID
- 4238126
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可