Application of Cardiac Gating to Improve the Reproducibility of Intravoxel Incoherent Motion Measurements in the Head and Neck
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- Kang Koung Mi
- Department of Radiology, Seoul National University Hospital Department of Radiology, Seoul National University College of Medicine
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- Choi Seung Hong
- Department of Radiology, Seoul National University Hospital School of Chemical and Biological Engineering, Seoul National University
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- Kim Dong Eun
- General Electronics (GE) Healthcare Korea
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- Yun Tae Jin
- Department of Radiology, Seoul National University Hospital Department of Radiology, Seoul National University College of Medicine
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- Kim Ji-hoon
- Department of Radiology, Seoul National University Hospital Department of Radiology, Seoul National University College of Medicine
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- Sohn Chul-Ho
- Department of Radiology, Seoul National University Hospital Center for Nanoparticle Research, Institute for Basic Science (IBS)
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- Park Sun-Won
- Department of Radiology, Seoul National University Boramae Hospital
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説明
<p>Purpose: To prospectively evaluate whether cardiac gating can improve the reproducibility of intravoxel incoherent motion (IVIM) parameters in the head and neck, we performed IVIM diffusion-weighted imaging (DWI) using 4 b values (4b), 4 b values with cardiac gating (4b gating) and 17 b values (17b).</p><p>Methods: We performed IVIM DWI twice per person on nine healthy volunteers using 4b, 4b gating and 17b and five patients with head and neck masses using 4b gating and 17b. The ADC, perfusion fraction (f), diffusion coefficient (D) and perfusion-related diffusion coefficient (D*) were calculated in the brain, masticator muscle, parotid gland, submandibular gland, tonsil and masses. Intraclass coefficient (ICC), Bland-Altman analysis (BAA) and coefficient of variation (CV) were used to assess short-term test-retest reproducibility. Kruskal-Wallis test and Mann-Whitney test were used to investigate whether 4b, 4b gating or 17b had significant influences on the parameters.</p><p>Results: For normal tissues and masses, ICC was excellent for all maps except the D* map. All parameters showed the lowest CV in the 4b gating. BAA also revealed the narrowest 95% limits of agreement using 4b gating for all parameters. In the subgroup analysis, almost all parameters in brain, muscle, parotid gland and submandibular gland showed the best reproducibility using 4b gating. In the muscle, parotid gland and submandibular gland, the values of ADC, f and D were not significantly different between among the three methods.</p><p>Conclusion: 4b gating was more reproducible with respect to measurements of IVIM parameters in comparison with 4b or 17b.</p>
収録刊行物
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- Magnetic Resonance in Medical Sciences
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Magnetic Resonance in Medical Sciences 16 (3), 190-202, 2017
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