Treatment of iatrogenic femoral artery pseudoaneurysms with US-guided low-dose thrombin injection

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  • 医原性仮性動脈瘤に対する超音波ガイド下低用量トロンビン注入療法

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Purpose: The traditional treatment of iatrogenic pseudoaneurysms required repair with surgery, US-guided compression repair (UGCR). US-guided thrombin injection (UGTI) has emerged as an alternative to sonographically guided compression repair. Studies have reported success rates since the late 1980s. This paper reviews 4 clinical cases in which we used UGTI to treat iatrogenic femoral pseudoaneurysms. Materials and Methods: From June 2005 through December 2008, we treated 4 patients with femoral artery pseudoaneurysms after angiography. A 23-gauge needle was placed into the lumen of the pseudoaneurysm under sonographic guidance, and an average dose of 100 U (range, 300-1,000 U) of thrombin was injected under continuous color-flow Doppler sonography. Injections were continued until the pseudoaneurysm thrombosed. Results: The average dose of thrombin was 575 U, a much smaller dose than previously reported. All 4 pseudoaneurysms were successfully thrombosed, and there were no complications. Conclusion: We reported 4 clinical cases. For the treatment of iatrogenic femoral pseudoaneurysms, US-guided thrombin injection is an effective treatment associated with a low rate of recurrence and few complications, even at lower doses of thrombin than previously reported.

Journal

  • Choonpa Igaku

    Choonpa Igaku 38 (1), 13-17, 2011

    The Japan Society of Ultrasonics in Medicine

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