環境化学物質の発達神経毒性研究における動物心理学の役割

DOI
  • 宮川 宗之
    独立行政法人労働安全衛生総合研究所健康障害予防研究グループ
  • 小川 園子
    筑波大学大学院人間総合科学研究科行動神経内分泌学研究室

書誌事項

タイトル別名
  • The role of animal psychology in developmental neurotoxicity assessment for environmental chemicals

抄録

This article describes background information for the symposium held at the 70th Annual meeting of the Japanese Society for Animal Psychology. The main theme of this symposium was to provide updated information on neurodevelopmental toxicity caused by environmental chemicals, through lectures by three distinguished researchers, and to discuss possible contributions and expected roles of animal psychology in toxicological studies designed to protect children's health. The Ministry of the Environment has commenced a large-scale, long-term epidemiological study entitled the “Environment and Children's Study (Eco-Chil)”, to elucidate health effects caused by chemical exposures of children including pervasive developmental disorders. Neurobehavioral assessments have been included in globally accepted guidelines for neurotoxicity and reproductive toxicity studies in rodents as effective tools for collecting experimental evidence. Findings from these experiments provide a scientific basis for the epidemiological studies, like Eco-Chil. However, currently available behavioral testing methods are insufficient for detecting neurodevelopmental effects of environmental chemicals, especially for emotionality and social aspects of behavior. Appropriate animal behavioral models are needed to advance toxicological studies further. Animal psychologists could greatly contribute to the development of these animal models and the interpretation of behavioral test results.

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詳細情報 詳細情報について

  • CRID
    1390282680184878848
  • NII論文ID
    130000780088
  • DOI
    10.2502/janip.61.1.7
  • ISSN
    18809022
    09168419
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • Crossref
    • CiNii Articles
    • KAKEN
  • 抄録ライセンスフラグ
    使用不可

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