新規モノテルペノイドホスホロチオネートおよび関連化合物の合成と抗菌活性

DOI NDLデジタルコレクション 日本農学文献記事索引 Web Site Web Site 被引用文献2件 参考文献4件

書誌事項

タイトル別名
  • Synthesis and Fungicidal Activity of New Thiophosphorylated Monoterpenoids and Related Compounds
  • Synthesis and Fungicidal Activity of Ne

この論文をさがす

説明

Isothymol, thymol and eugenol in the essential oil of Alpinia speciosa possess strong antifungal activity against plant pathogenic fungi. Although these active constituents are volatile in the natural environment, they can be changed into nonvolatile phosphorothionates by reaction with thiophosphoric agents using triethylamine or aq. NaOH as a base. Twenty-eight kinds of thiophosphorus esters were synthesized. During volatile testing, phenethyl alcohol and isothymol were almost volatilized in 9 and 14 days, respectively and eugenol was volatilized 89.2% in 14 days. Dimethyl isothymyl phosphorothionate (17), dimethyl eugenyl phosphorothionate (19), dimethyl phenethyl phosphorothionate (20), and diethyl phenethyl phosphorothionate (25) derived from each essential oil were scarcely volatilized and the volatility of 17, 19, 20, and 25 were 4.0, 2.3, 12.6, and 7.6% in 14 days, respectively. Among the synthesized compounds, 20 showed the strongest antifungal activity, 39.6 and 56.6% inhibition at 10ppm against Pythium sp. and Corticium rolfsii, respectively. Compound 20 had activity as potent as Iprobenfos.

収録刊行物

被引用文献 (2)*注記

もっと見る

参考文献 (4)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ