インダノファンとその鏡像異性体による超長鎖脂肪酸生合成の阻害

DOI NDLデジタルコレクション 日本農学文献記事索引 Web Site Web Site 参考文献10件
  • Kato Sachio
    Graduate School of Agricultural Science, Tamagawa University
  • Tanaka Akira
    Graduate School of Agricultural Science, Tamagawa University
  • Watanabe Hiroyuki
    Graduate School of Agricultural Science, Tamagawa University
  • Sato Yukiharu
    Graduate School of Agricultural Science, Tamagawa University
  • Ikeda Yumi
    Graduate School of Agricultural Science, Tamagawa University
  • Böger Peter
    Lehrstuhl für Physiologie und Biochemie der Pflanzen, Universität Konstanz
  • Wakabayashi Ko
    Graduate School of Agricultural Science, Tamagawa University

書誌事項

タイトル別名
  • Inhibitory Activity of Indanofan and Its Enantiomers on Biosynthesis of Very-Long-Chain Fatty Acids

この論文をさがす

説明

The influence of the S-enantiomer, R-enantiomer and racemate species of indanofan on the elongation of very-long-chain fatty acids (VLCFA) elongation was assayed using a leek microsomal preparation. Double-reciprocal plots of the rate of VLCFA production versus the concentration of C18 : 0-CoA demonstrated to be a competitive type of inhibition by indanofan. The I50 values of (S)-indanofan, (R)-indanofan and the (RS)-indanofan racemate for elongation of C18 : 0- and C20 : 0-acid were estimated to be about 2×10−8, >10−3 and 5×10−8 M, respectively. These findings prove that the S-enantiomer inhibited the elongation of the C18 : 0-and C20 : 0-acid ca. 2–3 times more strongly than the racemate, yielding almost no inhibition by the R-enantiomer. The elongation of C18 : 0- as well as of the C20 : 0-acid is inhibited by the S-enantiomer only. © Pesticide Science Society of Japan

収録刊行物

参考文献 (10)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ