Microdosimetric Evaluation of Secondary Particles in a Phantom Produced by Carbon 290 MeV/nucleon Ions at HIMAC
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- ENDO Satoru
- Research Institute for Radiation Biology and Medicine, Hiroshima University
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- TAKADA Masashi
- National Institute of Radiological Science
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- ONIZUKA Yoshihiko
- Department of Health Science, Kyushu University
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- TANAKA Kenichi
- Research Institute for Radiation Biology and Medicine, Hiroshima University
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- MAEDA Naoko
- Izumisano Hospital
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- ISHIKAWA Masayori
- Hokkaido University Hospital
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- MIYAHARA Nobuyuki
- National Institute of Radiological Science
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- HAYABUCHI Naofumi
- Department of Radiology, School of Medicine, Kurume University
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- SHIZUMA Kiyoshi
- Quantum Energy Applications, Graduate School of Engineering, Hiroshima University
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- HOSHI Masaharu
- Research Institute for Radiation Biology and Medicine, Hiroshima University
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Microdosimetric single event spectra as a function of depth in a phantom for the 290 MeV/nucleon therapeutic carbon beam at HIMAC were measured by using a tissue equivalent proportional counter (TEPC). Two types of geometries were used: one is a fragment particle identification measurement (PID-mode) with time of flight (TOF) method without a backward phantom, and the other is an in-phantom measurement (IPM-mode) with a backward phantom.<br> On the PID-mode geometry, fragments produced by carbon beam in a phantom are identified by the ΔE-TOF distribution between two scintillation counters positioned up- and down-stream relative to the tissue equivalent proportional counter (TEPC). Lineal energy distributions for carbon and five ion fragments (proton, helium, lithium, beryllium and boron) were obtained in the lineal-energy range of 0.1-1000 keV/μm at eight depths (7.9-147.9 mm) in an acrylic phantom. In the IPM-mode geometry, the total lineal energy distributions measured at eight depths (61.9-322.9 mm) were compared with the distributions in the PID-mode. Both spectra are consistent with each other. This shows that the PID-mode measurement can be discussed as the equivalent of the phantom measurement. The dose distribution of the carbon beam and fragments were obtained separately. In the depth dose curve, the Bragg peak was observed.<br> Relative biological effectiveness (RBE) for the carbon beam in the acrylic phantom was obtained based on a biological response function as a lineal-energy. The RBE of carbon beam had a maximum of 4.5 at the Bragg peak. Downstream of the Bragg peak, the RBE rapidly decreases. The RBE of fragments is dominated by Boron particles around the Bragg peak region.<br>
収録刊行物
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- Journal of Radiation Research
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Journal of Radiation Research 48 (5), 397-406, 2007
Journal of Radiation Research 編集委員会
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詳細情報 詳細情報について
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- CRID
- 1390282680191914880
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- NII論文ID
- 110006388622
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- NII書誌ID
- AA00705792
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- ISSN
- 13499157
- 04493060
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- NDL書誌ID
- 8911810
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- NDL-Digital
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可