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- TORIKOSHI Masami
- Department of Accelerator and Medical Physics, National Institute of Radiological Sciences
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- MINOHARA Shinichi
- Department of Accelerator and Medical Physics, National Institute of Radiological Sciences
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- KANEMATSU Nobuyuki
- Department of Accelerator and Medical Physics, National Institute of Radiological Sciences
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- KOMORI Masataka
- Department of Accelerator and Medical Physics, National Institute of Radiological Sciences
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- KANAZAWA Mitsukata
- Department of Accelerator and Medical Physics, National Institute of Radiological Sciences
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- NODA Koji
- Department of Accelerator and Medical Physics, National Institute of Radiological Sciences
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- MIYAHARA Nobuyuki
- Department of Accelerator and Medical Physics, National Institute of Radiological Sciences
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- ITOH Hiroko
- Department of Accelerator and Medical Physics, National Institute of Radiological Sciences
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- ENDO Masahiro
- Department of Accelerator and Medical Physics, National Institute of Radiological Sciences
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- KANAI Tatsuaki
- Department of Accelerator and Medical Physics, National Institute of Radiological Sciences
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抄録
Clinical trials of carbon radiotherapy started at HIMAC in 1994 using three treatment rooms and four beam ports, two horizontal and two vertical. The broad beam method was adopted to make a three-dimensionally uniform field at an isocenter. A spot beam extracted from an accelerator was laterally spread out by using a pair of wobbler magnets and a scatterer. A bar ridge filter modulated the beam energy to obtain the spread out Bragg peak (SOBP). The SOBP was designed to be flat in terms of the biological dose based on the consideration that the field consisted of various beams with different LET. Finally, the field of 20 cm in diameter with ± 2.5% uniformity was formed at the isocenter. The width of the maximum SOBP was 15 cm. When treating the lung or liver, organs that move due to breathing, the beam was irradiated only during the expiration period in a respiration-gated irradiation method. This reduced the treatment margin of the moving target. In order to prevent normal tissues adjacent to the target volume from irradiation by an unwanted dose, a layer-stacking method was developed. In this method, thin SOBP layers which have different ranges were piled up step by step from the distal end to the entrance of the target volume. At the same time, a multi-leaf collimator was used to change the aperture shape to match the shape of each layer to the cross-sectional shape of the target. This method has been applied to rather large volume cancers including bone and soft-tissue cancers. Only a few serious problems in the irradiation systems have been encountered since the beginning of the clinical trials. Overall the systems have been working stably and reliably.<br>
収録刊行物
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- Journal of Radiation Research
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Journal of Radiation Research 48 (Suppl.A), A15-A25, 2007
Journal of Radiation Research 編集委員会
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詳細情報 詳細情報について
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- CRID
- 1390282680194764160
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- NII論文ID
- 110006273206
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- NII書誌ID
- AA00705792
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- ISSN
- 13499157
- 04493060
- http://id.crossref.org/issn/04493060
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- NDL書誌ID
- 8735792
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- NDL-Digital
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可