The Protective Efficacy of Dietary Supplements on Metabolic Syndrome

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  • YASUKAWA Ken
    Laboratory of Self Medication, School of Pharmacy, Nihon University
  • OGAWA Kouichi
    Laboratory of Self Medication, School of Pharmacy, Nihon University
  • TSUDA Yurika
    Laboratory of Self Medication, School of Pharmacy, Nihon University
  • MATSUBARA Hideki
    Laboratory of Self Medication, School of Pharmacy, Nihon University

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  • サプリメントのメタボリックシンドローム予防効果
  • サプリメント ノ メタボリックシンドローム ヨボウ コウカ

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Abstract

Objective: To show the preventive effect of dietary supplements on metabolic syndrome.<br> Methods: Twenty dietary supplements were examined for inhibition of α-glucosidase, absorption of sugar in mice, lipids accumulation and adiponectin production in rat visceral adipocytes.<br> Results: In twenty dietary supplements, Bombyx mori and mulberry leaves inhibited rat intestinal α-glucosidase more than acarbose, and inhibited absorption of sugar in mice. In visceral adipocytes, Ganoderma lucidum, mate and Japanese yew inhibited accumulation of lipid and Artemisia Capillaris Flowers and Ground-ivy increased production of adiponectin in rat visceral adipocytes.<br> Conclusion: Mulberry leaves, Bombyx mori, Glechoma hederacea, Artemisia Capillaris Flowers are natural products which offer promise in the prevention of diabetes and metabolic syndrome. Incorporating dietary supplements into a treatment plan with medicines with similar effects requires further study.<br>

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