Mutagenicity Test for Hot Water Extract of Coix lacryma-jobi L. var. ma-yuen Stapf -Reverse Mutation Test, Mouse Lymphoma Assay (MLA) and Mouse Micronucleus Test
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- HAYASHI Hirotaka
- Center for Innovation, Kanazawa University Department of Complementary and Alternative Medicine Clinical Research and Development, Kanazawa University
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- ISHIBASHI Norihito
- Biotherapy Development Research Center Co., Ltd.
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- OHTA Mayumi
- Biotherapy Development Research Center Co., Ltd.
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- ARAI Takanari
- Endowed Center for the Advancement of Pregnancy, Perinatal and Infant Care, Kanazawa University Graduate School of Medical Science
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- SHIGETA Yuko
- Department of Complementary and Alternative Medicine Clinical Research and Development, Kanazawa University
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- STRONG Jeffry M
- Department of Complementary and Alternative Medicine Clinical Research and Development, Kanazawa University
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- OHTA Tomihisa
- Graduate School of Natural Science and Technology, Kanazawa University
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- SUZUKI Nobutaka
- Department of Complementary and Alternative Medicine Clinical Research and Development, Kanazawa University
Bibliographic Information
- Other Title
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- ハトムギ熱水抽出物の変異原性試験 ‐復帰変異試験，マウスリンフォーマ試験 （ＭＬＡ），マウス小核試験‐
- ハトムギ熱水抽出物の変異原性試験--復帰変異試験,マウスリンフォーマ試験(MLA),マウス小核試験
- ハトムギ ネッスイ チュウシュツブツ ノ ヘンイゲンセイ シケン フッキ ヘンイ シケン マウスリンフォーマ シケン MLA マウス ショウカク シケン
- —Reverse Mutation Test, Mouse Lymphoma Assay (MLA) and Mouse Micronucleus Test
- ―復帰変異試験，マウスリンフォーマ試験 (MLA)，マウス小核試験―
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Abstract
Coix lacryma-jobi L. var. ma-yuen Stapf is a grass long been used in traditional medicine as a nourishing food and reported to possess pharmacological effects including anti-tumor, anti-obesity, anti-diabetic, etc. In order to evaluate the possible mutagenicity of the hot water extract of all parts (husks, pellicles, and astringent skin) of the food, we performed a reverse mutation test in bacteria, a mouse lymphoma assay and a mouse micronucleus test. The results of all tests were negative. It was concluded that the extract has no mutagenicity for living bodies.<br>
Journal
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- Japanese Journal of Complementary and Alternative Medicine
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Japanese Journal of Complementary and Alternative Medicine 6 (3), 157-162, 2009
The Japanese Society for Complementary and Alternative Medicine
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Details 詳細情報について
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- CRID
- 1390282680197441280
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- NII Article ID
- 130000129052
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- NII Book ID
- AA12095429
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- ISSN
- 13487930
- 13487922
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- NDL BIB ID
- 10490873
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- Text Lang
- ja
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- Data Source
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- JaLC
- IRDB
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed