Urgent radical resection of locoregionally advanced anaplastic thyroid carcinoma -A report of two cases

DOI 1 Citations 17 References
  • Omura Go
    Department of Head and Neck Surgery, Saitama Medical University International Medical Center
  • Takajo Fumihiko
    Department of Head and Neck Surgery, Saitama Medical University International Medical Center
  • Morita Kei
    Department of Head and Neck Surgery, Saitama Medical University International Medical Center
  • Abe Takahiro
    Department of Head and Neck Surgery, Saitama Medical University International Medical Center
  • Nakahira Mitsuhiko
    Department of Head and Neck Surgery, Saitama Medical University International Medical Center
  • Yokogawa Hideki
    Department of Plastic Surgery, Saitama Medical University International Medical Center
  • Hirokawa Eiko
    Department of Plastic Surgery, Saitama Medical University International Medical Center
  • Nakatsuka Takashi
    Department of Plastic Surgery, Saitama Medical University International Medical Center
  • Sugasawa Masashi
    Department of Head and Neck Surgery, Saitama Medical University International Medical Center

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Other Title
  • 準緊急的な拡大切除で局所制御をしえた進行甲状腺未分化癌の２症例

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Description

Anaplastic thyroid carcinoma (ATC) is one of the most aggressive malignancies. Its prognosis is extremely poor, and many reports described that complete resection of the tumor showed better locoregional control. We urgently performed radical resection in two patients with locoregionally advanced ATC within 10 days after the first visit.<br>Case 1: A 63-year-old man presented with a rapidly growing thyroid mass that had been noticed one month earlier. The cytologic examination performed at the previous clinic showed ATC. He was referred to our hospital for treatment of the disease. Ten days after the first visit, a total thyroidectomy combined with total laryngectomy and bilateral neck dissection was performed. He has been alive for 27 months with no evidence of disease.<br>Case 2: A 66-year-old woman suffered from right neck pain, and had noticed a rapidly growing thyroid mass one month earlier. At the previous clinic, her thyroid mass was diagnosed as ATC by cytologic examination. Seven days after visiting our hospital, a total thyroidectomy in conjunction with total laryngopharyngoesophagectomy and bilateral neck dissection was performed, and her gullet was reconstructed with a free jejunum. She received 54 Gy of irradiation postoperatively. However, multiple metastases developed 4 months later, and she died 5 months after the operation without local recurrence.<br>For ATC, radical complete dissection for locoregional control should be performed as soon as possible due to the possibility of cure and airway management.

Journal

  • Toukeibu Gan

    Toukeibu Gan 37 (1), 83-87, 2011

    Japan Society for Head and Neck Cancer

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