Reexamination of the Validity and Reliability of the Japanese Version of the Mini-Mental State Examination (MMSE-J)

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  • 精神状態短時間検査-日本版(MMSE-J)の妥当性と信頼性に関する再検討
  • セイシン ジョウタイ タンジカン ケンサ-ニホンバン(MMSE-J)ノ ダトウセイ ト シンライセイ ニ カンスル サイケントウ

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<p>The criterion-based validity of the Japanese version of the Mini Mental State Examination(MMSE-J) (Sugishita 2006) was preliminarily evaluated in 2010(Sugishita, Hemmi and JADNI 2010) based on data from 313 subjects who participated in the Japanese Alzheimer’s Disease Neuroimaging Initiative (J-ADNI). Test-retest reliability was also preliminarily examined in 145 subjects in J-ADNI who were tested twice. The second testing was performed 6 months after the first(Sugishita, Hemmi and JADNI 2010). However, in March, 2012, an employee of a pharmaceutical company reported that the J-ADNI data for some subjects had been falsified. In March, 2014, Drs. Sugishita, M and Asada,T reported a total of 105 cases with confirmed or suspected falsification of data or protocol violation (68 cases by Sugishita and 37 cases by Asad) to the Special Investigative Committee of the University of Tokyo. In June 20, 2014, the Committee confirmed that data had been inappropriately modified by inappropriate persons.</p><p>The authors (Sugishita & Hemmi) of the 2010 paper (Sugishita, Hemmi and JADNI 2010)then proposed to withdraw and revise the paper. The editorial board of the Japanese Journal of Cognitive Neuroscience accepted the proposal on June 3, 2014. In October 2014, 129 cases with confirmed or suspected falsification of data or protocol violation were reported to the Third Party Panel of the University of Tokyo. The Third Party Panel examined all 129 subjects and found no falsification of data or protocol violations. However, the four written refutations by Dr. M. Sugishita argued against the criticism of the Third Party Panel and it became clear that the Third Party Panel had made errors in judgment (cf. http://www.geocities.jp/shinjitunodentatu/daisannsyaiin.html). Consequently, it is necessary to exclude the subjects with falsification of data or protocol violation from the J-ADNI data. However, Dr. T. Iwatsubo (the J-ADNI principal investigator) disclosed under limitations the uncorrected J-ADNI data to researchers through the Japan Science and Technology Information Aggregator, Electronic (J-STAGE) in January 2016 (http://humandbs.biosciencedbc.jp/hum0043-v1). Therefore, the aim of the present study was to reexamine the validity and reliability of the MMSE-J after excluding cases with confirmed or suspected falsification of data or protocol violations.</p><p>(View PDF for the rest of the abstract.)</p>

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