Relationship between sleep disorders and dementia

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  • Inoue Yuichi
    Department of Somnology, Tokyo Medical University Japan Somnology Center, Neuropsychiatric Research Institute, Tokyo, Japan

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  • 認知症と睡眠障害
  • 教育講演 認知症と睡眠障害
  • キョウイク コウエン ニンチショウ ト スイミン ショウガイ

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<p>Sleep disorder is very common in population affected with dementia.　Although fragmentation and shallowing of nocturnal sleep are relatively common among dementia disorders, some specific abnormalities are present in respective dementia disorders, i.e. patients with Alzheimer type dementia are likely to show decreased amplitude of circadian rhythm leading to irregular sleep awake schedule and patients with Lewy body dementia frequently have dysfunction of the control of muscle tonus during REM sleep which may cause dream enactment abnormal behavior in this sleep stage.　For prevention of the appearance as well as the development of dementia, appropriate management of insomnia would be necessary.　However, usage of hypnotics （benzodiazepines and its agonists） in demented population may become a risk factor for falls, nocturnal delirious behavior and enhancement of cognitive dysfunction in the affected population.　In addition, we want to emphasize the necessity of proper management of obstructive sleep apnea syndrome, a common disorder in the elderly, would be desirable in individuals with dementia, since the disorder may become a risk factor for causing cerebrovascular events during sleep and for the aggravation of cognitive decline in this population.</p>

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