Treatment of Cancer and Palliative Care (6) Pharmacokinetics and Pharmacodynamics of Antineoplastic Agents

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  • Suzuki Ai
    Department of Pharmaceutical Service, Nippon Medical School Hospital
  • Ise Yuya
    Department of Pharmaceutical Service, Nippon Medical School Hospital
  • Katayama Shirou
    Department of Pharmaceutical Service, Nippon Medical School Hospital

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Other Title
  • がん医療と緩和ケア（6）
  • がん医療と緩和ケア(6)抗がん剤の薬物動態と薬力学について : エルロチニブを例として
  • ガン イリョウ ト カンワ ケア(6)コウガンザイ ノ ヤクブツ ドウタイ ト ヤクリキガク ニ ツイテ : エルロチニブ オ レイ ト シテ
  • 抗がん剤の薬物動態と薬力学について～エルロチニブを例として～

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Abstract

Basic research has produced a wealth of knowledge regarding the molecular mechanisms of cancer development, and antineoplastic agents that target specific molecules have been developed. These agents have the potential to revolutionize cancer management in terms of the risk/benefit ratio of treatment. This review article provides general concepts of pharmacokinetics and pharmacodynamics data of molecularly targeted agents, e.g. erlotinib. Erlotinib is an epidermal growth factor receptor tyrosine kinase inhibitor that has been used to treat nonsmall cell lung cancer and pancreatic cancer.

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