Diagnosis of Diabetes Based on Fasting Plasma Glucose and Hemoglobin A1c

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  • 空腹時血糖およびHbA1cからみた耐糖能異常の診断
  • クウフクジ ケットウ オヨビ HbA1c カラ ミタ タイトウノウ イジョウ ノ シンダン

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Abstract

Objective: The purpose of this retrospective cohort study was to evaluate the relationship between oral-glucose tolerance tests (OGTT) and fasting plasma glucose (FPG) + hemoglobin A1c (HbA1c, JDS-value).<br>Methods: A total of 1,036 health check-up examinees were enrolled in the present study. They were examined for FPG, HbA1c, and OGTT at the same time.<br>Results: 1. Of 782 subjects with a FPG of ≤ 99 mg/dL, 9 (1.2 %) had an HbA1c level of 5.9 % ≤. 2. Four (0.9%) of 470 subjects with a FPG of ≤ 99 mg/dL and HbA1c of ≤ 5.1 % had “ OGTT 2hr-value ≥ 200mg/dL ” and 55 (11.7%) had “ 140 ≤ OGTT 2hr-value < 200mg/dL: impaired glucose tolerance (IGT) ” 3. Eleven (3.3%) of 326 subjects with FPG of 100 mg/dL ≤ or HbA1c of 5.2 % ≤ had “ OGTT 2hr-value ≥ 200mg/dL ” and 75 had IGT(23 %). 4. Eighty-three (35.0%)of 240 subjects with an FPG of 100 mg/dL ≤ and HbA1c of 5.2 % ≤ had “ OGTT 2hr-value ≥ 200mg/dL ” and 87 (36 %) had IGT.<br>Conclusion: The present study indicates that examining both FPG and HbA1c is important, and that people with an FPG of 100 mg/dL ≤ or HbA1c of 5.2 % ≤ should be given OGTT.

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