Clinical Features of Patients with Gallstones Detected in Health Check-up

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  • 人間ドック受診者における胆石保有者の特徴
  • ニンゲン ドック ジュシンシャ ニ オケル タンセキ ホユウシャ ノ トクチョウ

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Objective: We investigated the characteristics of persons in whom gallstones had been detected in health check-up of a healthy population in order to identify lifestyle changes likely to decrease gallstone risk.<br>Methods: We performed a health evaluation including abdominal ultrasonography of 23,848 people at our institution in 2009. We compared persons with and without gallstones with respect to age, gender, body mass index (BMI), diabetes (HbA1c), lipid metabolism, liver function, other laboratory parameters, lifestyle, lifestyle-related diseases and ultrasonographic findings. Concerning BMI, laboratory data and lifestyle-related diseases, we divided the subjects into 3 groups by age; under 40 years old, 41 to 59 years old, and over 60 years old.<br>Results: The gallstone detection rate was 4.5%. The mean age of those with stones was significantly higher than that of those without. The mean BMI of subjects with stones was significantly higher than that of those without for all age groups. The HbA1c of over 60-year-old and 41 to 59-year-old subjects was significantly higher than that of under 40-year-old ones. Serum triglycerides were significantly higher in persons with stones than that in those without. No significant differences were evident between the two groups in other laboratory parameters. No significant differences were found for exercise, smoking, or sleep, but prevalence of gallstones among people who did not drink was significantly higher than in both those who drank moderate and larger quantities of alcohol. Ultrasonographic findings such as adenomyomatosis and gallbladder wall thickening were seen more frequent in subjects with stones. <br>Conclusion: Lowering excessive blood triglycerides, reducing obesity and adequate alcohol consumption may be effective in decreasing the risk of gallstones.

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