Assessment of Cut-off Point of Hemoglobin A1c in Health Check-up for Metabolic Syndrome.

DOI Web Site 17 References

Bibliographic Information

Other Title
  • メタボリック健診で用いられるヘモグロビンAlcのCut-off値についての検討
  • メタボリック健診で用いられるヘモグロビン A1cのCut-off値についての検討
  • メタボリック ケンシン デ モチイラレル ヘモグロビン A1c ノ Cut offチ ニ ツイテ ノ ケントウ

Search this article

Description

Objective: Japanese ministry of health, labor and welfare starts health check-up which is specialized for metabolic syndrome since April,2008. In the new health check-up, the alternative clinical examinations which detect minimal glucose intolerance are hemoglobin Ai (HbA1c) or FPG. We evaluated the optimum cutoff point of HbA1c for metabolic syndrome. Material and Method: The study subjects consisted of 1018 men and 661 women who underwent health check-ups including FPG, HbA1c and erythrocyte indices in our facility. We investigated factors that were attributable to influence on HbAi in 1023subjects with FPG below 100 mg/c11C. onsidering the factors, we presume optimum cutoff point of HbAi to detect FPG over 100 mg/di according to analysis of receiver operating characteristic (ROC) curves. Results: In the subjects with FPG bellow 100 mg/d1, the values of HbA1c of women were 0.1% higher than those of men on any FPG levels. Multiple regression analysis revealed that FPG and age were positive independent factors for HbA1c, and hemoglobin and mean corpuscular volume (MCV) were negative independent factors. Considering gender, ROC curves showed that optimum cutoff points of HbA1c to detect FPG 100 mg/di were 5.2% for men,5.3% for women. Conclusion: Women had higher HbA1c levels than men due to the tendency of iron deficiency. The cutoff point of HbAi should be higher in women than in men.

Journal

References(17)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top