A Long-Time, High Spatiotemporal Resolution Optical Recording System for Membrane Potential Activity via Real-Time Writing to the Hard Disk

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  • Hirota Akihiko
    Department of Neural and Muscular Physiology, Shimane University School of Medicine
  • Ito Shin-ichi
    Department of Neural and Muscular Physiology, Shimane University School of Medicine

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  • Long Time High Spatiotemporal Resolution Optical Recording System for Membrane Potential Activity via Real Time Writing to the Hard Disk

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Using real-time hard disk recording, we have developed an optical system for the long-duration detection of changes in membrane potential from 1,020 sites with a high temporal resolution. The signal-to-noise ratio was sufficient for analyzing the spreading pattern of excitatory waves in frog atria in a single sweep.<br>

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