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Studies on Antibiotics. XVI. Isolation and Identification of Dihydrostreptomycin produced by a New Streptomyces, Streptomyces humidus nov. sp.
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Description
Isolation and chemical studies were carried out on an antibiotic which was produced by a new streptomyces, Streptomyces humidus nov. sp. From the physical, chemical, and microbiological properties of this antibiotic in crude state, it was found that this antibiotic belonged to the so-called streptomycin-group antibiotics, but differed from streptomycin, mannosidostreptomycin, and hydroxystreptomycin, which are produced directly by streptomycetes. This antibiotic was finally isolated as a pure crystalline sulfate. The physicochemical and microbiological properties of this sulfate and physicochemical properties of its degradation products showed that this sulfate was nothing but dihydrostreptomycin sulfate.
Journal
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- Pharmaceutical Bulletin
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Pharmaceutical Bulletin 5 (4), 343-349, 1957
The Pharmaceutical Society of Japan
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Keywords
Details 詳細情報について
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- CRID
- 1390282680237798272
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- NII Article ID
- 130003549248
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- COI
- 1:CAS:528:DyaG1cXot1eqtQ%3D%3D
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- ISSN
- 18811345
- 03699471
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- PubMed
- 13494129
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- Text Lang
- en
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- Article Type
- journal article
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- Data Source
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed