書誌事項
- タイトル別名
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- A Simulation Method of Cell Physiological Experiments with a Novel Description Language for Experimental Protocols
- キジュツ ゲンゴ オ モチイタ サイボウ セイリガク ジッケン シミュレーション シュホウ
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抄録
For computer simulations of physiological experiments by physiological models, a machine-readable description of experimental protocols is useful. Although description formats for cell physiological models are already available, there is no specialized representation format for experimental protocols. Here, we propose an XML-based language, PEPML (Physiological Experimental Protocol Markup Language), and a simulation method of experimental protocols in PEPML. In the PEPML, conditions and procedures of an experimental protocol are procedurally described as a list of events, each of which consists of a condition for execution and an action to be executed. By specifying the references of variables in a protocol using an ontology, the protocol can be applied to various models without editing tasks. The proposed simulation method allows unambiguous numerical calculation of a procedural experimental protocol, which is applied to a declaratively represented model by interpretation of the protocol as a set of boundary conditions for the model variables. PEPML and the proposed method allow applying both multiple protocols to a single model and a single protocol to multiple models. This feature facilitates the efficient simulation for verification, comparison and utilization of physiological models.
収録刊行物
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- 生体医工学
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生体医工学 46 (1), 77-84, 2008
公益社団法人 日本生体医工学会
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詳細情報 詳細情報について
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- CRID
- 1390282680243060608
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- NII論文ID
- 110006649739
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- NII書誌ID
- AA11633569
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- ISSN
- 18814379
- 1347443X
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- NDL書誌ID
- 9480378
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可
