Visualization of Thrombus Formation Process and Flow Analysis on Shear Blood Flow

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  • FUKUSHIMA Katsuya
    Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology
  • TAMAGAWA Masaaki
    Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology
  • HIRAMOTO Miki
    Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology

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Other Title
  • せん断流れ場における血栓形成の可視化
  • センダン ナガレバ ニ オケル ケッセン ケイセイ ノ カシカ

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This paper describes the visualization of thrombus formation process by using the plasma water to develop the CFD based prediction method of thrombus formation. The experimental apparatus has one orifice pipe that is a simplified model of shear flow in the rotary blood pumps and the stent device. In the first step, the flow in the orifice pipe flow is analyzed by CFD and the shear rate distribution is shown in the case of steady and pulsate flow. In the second step, the thrombus formation process is visualized for constructing the prediction model of thrombus formation. The feature of the experiment is to observe the thrombus formation process by image processing and to quantify the index of thrombus by using blood plasma. Comparing the experimental result with CFD-based shear rate distribution, it is found that the early thrombus is generated at the part where the shear rate of the orifices is high, and the formation speed is dependent on the gradient of shear rate, and the temperature the test circuit.

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