A Simple Assessment Method of Red Blood Cell Fragility

DOI

Bibliographic Information

Other Title
  • 赤血球脆弱性の簡易評価に関する研究

Abstract

This study proposes a simple optical method for assessing red blood cell (RBC) fragility. A sodium citrate-added porcine blood was centrifuged. The RBCs contained in the upper and lower 3% of the RBC layer were collected and each sample of 1.5μL was added to saline of 0.75mL. Here we call these samples U and L groups, respectively. Each sample was added to distilled water of 0.75mL to expose the RBCs to low osmolality. The time variation in the optical power transmitted through the sample was approximated with a first order lag function and the time constant was calculated. The mean time constants of U and L groups were 20.5s and 16.3s, respectively. The difference of the time constant seems to reflect the mean fragility of RBCs contained in the samples. Furthermore, the change in the volume distribution of RBCs was also considered through the frequency analysis of the output signal.

Journal

Details 詳細情報について

  • CRID
    1390282680243734656
  • NII Article ID
    130004695895
  • DOI
    10.11239/jsmbe.52.o-531
  • ISSN
    18814379
    1347443X
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

Report a problem

Back to top