Automatic Measurement of Axial Length of Human Eye using Three-Dimensional Magnetic Resonance Imaging

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  • WATANABE Masaki
    Center for Integrated Human Brain Science, Brain Research Institute, University of Niigata Graduate School of Science and Technology, Niigata University
  • KIRYU Tohru
    Graduate School of Science and Technology, Niigata University

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Other Title
  • 3次元MRI画像によるヒト眼軸長自動測定
  • 3ジゲン MRI ガゾウ ニ ヨル ヒトガンジクチョウ ジドウ ソクテイ

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The measurement of axial length and the evaluation of three dimensional (3D) form of an eye are essential to evaluate the mechanism of myopia progression. We propose a method of automatic measurement of axial length including adjustment of the pulse sequence of short-term scan which could suppress influence of eyeblink, using a magnetic resonance imaging (MRI) which acquires 3D images noninvasively. Acquiring T2-weighted images with 3.0 tesla MRI device and eight-channel phased-array head coil, we extracted left and right eye ball images, and then reconstructed 3D volume. The surface coordinates were calculated from 3D volume, fitting the ellipsoid model coordinates with the surface coordinates, and measured the axial length automatically. Measuring twenty one subjects, we compared the automatically measured values of axial length with the manually measured ones, then confirmed significant elongation in the axial length of myopia compared with that of emmetropia. Furthermore, there were no significant differences (p<0.05) between the means of automatic measurements and the manual ones. Accordingly, the automatic measurement process of axial length could be a tool for the elucidation of the mechanism of myopia progression, which would be suitable for evaluating the axial length easily and noninvasively.

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