Study of the upper limb blood pressure changes by vascular resistance increase of the lower limbs using entire cardiovascular system

  • Akama Yusuke
    Biomedical Engineering, Graduate School of Engineering, Tokyo City University Graduate School
  • Kayanuma Hiroshi
    Biomedical Engineering, Graduate School of Engineering, Tokyo City University Graduate School
  • Yauchi Shiori
    Biomedical Engineering, Graduate School of Engineering, Tokyo City University Graduate School
  • Hirayama Kodai
    Biomedical Engineering,Faculty of Engineering, Tokyo City University
  • Ohshima Mari
    Graduate School of Interdisciplrinary Information Studies,The University of Tokyo
  • Sugawara Motoaki
    Medical Engineering, Faculty of Health Care Sciences Himeji Dokkyo University
  • Niki Kiyomi
    Biomedical Engineering, Graduate School of Engineering, Tokyo City University Graduate School

Bibliographic Information

Other Title
  • 全身循環シミュレーションを用いた下肢の末梢血管抵抗変化時の上肢血圧の検討

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Description

<p>Hypertension treatment is important to prevent cardiovascular disease. The simulation model has potential to be applied to the treatment. In this study, we evaluated changes in upper limb's blood pressure by increasing lower limb's vascular resistance with simulation model and compared them with human data. We used entire cardiovascular system as a computational model. The arterial system was consisted of 88 vessels coupled with a lumped parameter model, which contains peripheral vessels and capillaries. The brachial blood pressure changes were caused by increasing vascular resistance of the tibial artery. Actual measurements were carried out by cold stimulation to the lower limbs.As results, the simulated data showed the blood pressure increase from 136 / 76 to 143 / 80 mmHg, which were similar to the human data (from 123/66 to 129/73 mmHg) [Conclusion] The entire simulation model recreated pressure change of upper limbs caused by vascular resistance increase of different artery.</p>

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Details 詳細情報について

  • CRID
    1390282680244552448
  • NII Article ID
    130005285310
  • DOI
    10.11239/jsmbe.54annual.s220
  • ISSN
    18814379
    1347443X
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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