複数皮質活動の動的イメージングのためのfMRI-MEG統合解析法

書誌事項

タイトル別名
  • An fMRI-MEG Integrative Method for Dynamic Imaging of Multiple Cortical Activities
  • フクスウ ヒシツ カツドウ ノ ドウテキ イメージング ノ タメ ノ fMRI MEG トウゴウ カイセキホウ

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抄録

We have developed an fMRI-MEG integrative method that is capable of analyzing spatiotemporal multiple cortical activities. Firstly, activated regions were determined by statistically analyzing fMRI data. Secondly, using fMRI analysis results as a spatial constraint, the location and orientation of equivalent current dipoles (ECD) were estimated by a procedure that maximizes the inner product of lead field and measured field vectors. The time-varying dipole moment was obtained by projecting the optimized lead field vector to measured fields. We applied the technique to data obtained during a visual perception task. An apparent motion stimulus that activates both primary and secondary visual areas (V1/2) and V5 was used in the experiment. Event-related neuromagnetic fields were measured by a 306-channel MEG system, whereas the fMRI data were acquired by a 1.5 T MR system. The present fMRI-MEG integrative analysis method successfully detected dynamic cortical activities in V1/2 and V5.

収録刊行物

  • 生体医工学

    生体医工学 43 (4), 777-784, 2005

    公益社団法人 日本生体医工学会

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