Development of Synthetic Vaccines against Antitumour and HIV having Lipid A Analogs as a Synthetic Immunoadjuvant.

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  • 細菌内毒素リピドＡ類を免疫アジュバント部位とする癌，エイズ合成ワクチンへの基礎研究
  • サイキンナイ ドクソ リピド Aルイ オ メンエキ アジュバント ブイ ト ス

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Abstract

This article describes our recent development of completely synthetic vaccines based on tumour- and HIV-associated carbohydrate and peptide antigens having N-tetradecanoyl L-seryl-β-alanine-containing D-glucosamine derivatives structurally related to lipid A as efficient synthetic immunoadjuvants.

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