バイオフィルター用テーラーメイド細孔構造を有する窒化ケイ素多孔体の開発 I V.透水性とバイオコンパティビリティーの評価

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  • Development of Porous Silicon Nitride with Tailor-Made Pore Structure for Bio-Filter: IV. Evaluation of permeability and bio-compatibility
  • バイオフィルターヨウ テーラーメイドサイコウ コウゾウ オ ユウスル チッカ ケイソ タコウタイ ノ カイハツ IV.トウスイセイ ト バイオコンパティビリティー ノ ヒョウカ

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抄録

In order to develop the<tt>“</tt> Bio-filter<tt>”</tt>, silicon nitride porous bodies with micro-macro complex pore structure were fabricated using the tape casting process. It was confirmed that the permeability of the macro pore (about 100 microns) was good enough for the waste water with high concentration of organic compounds, while that of the micro pore (about 1 micron) showed much less permeability even for distilled water. The bio-compatibility of betasilicon nitride porous body was first investigated in this study. Small specimens of the silicon nitride porous bodies with or without the surface treatment of amino-silane coupling agents were immersed in the cell culture liquid containing the two kinds of microbes, Saccharomyces cerevisiae and Lactobacillus casei. After several days, their surfaces and fracture surfaces were observed using a scanning electron microscope, and the numbers of microbes fixed on the surfaces were counted. It was found that all specimens fixed certain amounts of both microbes, and no difference in the average number of fixed microbes per unit area was confirmed between specimens with or without the silane surface treatments, which suggests that the surface of beta-silicon nitride crystal possess good biocompatibility. The large average numbers of fixed microbes per unit area was confirmed only when the bio-films existed on the surfaces, suggesting the possible formation of the microbe consortium.

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  • 資源と素材

    資源と素材 129 (5), 165-170, 2013

    一般社団法人 資源・素材学会

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