A Case of Lung Cancer with Chest Wall Invasion Showed a Pathologically Complete Response to Preoperative Thermo-chemo-radiotherapy

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  • TERASHIMA KOTARO
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University
  • SHIOYAMA YOSHIYUKI
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University
  • NOMOTO SATOSHI
    Department of Radiology, Fukuoka University
  • OHGA SAIJI
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University
  • NONOSHITA TAKESHI
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University
  • YOSHITAKE TADAMASA
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University
  • OHNISHI KAYOKO
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University
  • ASAI KAORI
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University
  • MATSUMOTO KEIJI
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University
  • TAKAYAMA KOICHI
    Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University
  • NAKAMURA KATSUMASA
    Department of Radiology, Kyushu University Hospital at Beppu
  • TERASHIMA HIROMI
    Department of Radiology, Harasanshin Hospital
  • HONDA HIROSHI
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University

Bibliographic Information

Other Title
  • 術前温熱化学放射線療法が著効し組織学的に完全奏功が証明された原発性肺癌の一例

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Abstract

A case of lung cancer with chest wall invasion treated by preoperative thermo-chemo-radiotherapy revealed a histologically complete response after complete resection is reported.<BR> A 55-year-old male was diagnosed as primary lung cancer originating from the right upper lobe, cT3N0M0, stage IIB. The tumor invaded the right chest wall accompanied with obstructive pneumonia at its dorsal side and was rapidly growing. Thus, preoperative thermo-chemo-radiotherapy was performed. He was treated with conventional irradiation with a 10 MV X-ray, a total dose of 40 Gy, and concurrent chemotherapy with cisplatin (CDDP) and vinorelbine (VNR). Hyperthermia was applied within 30 min after each radiotherapy with a RF-capacitive heating apparatus (Thermotron RF-8, Ymamamoto Vinyter, Osaka, Japan), 40 min/time, once a week, for a total of 4 times. The tumor revealed necrotic change on CT images after thermo-chemo-radiotherapy and was completely resected. No viable cancer cells were observed in the histological examination (Ef 3). Even 17 months later, there was no recurrence.

Journal

  • Thermal Medicine

    Thermal Medicine 27 (1), 25-30, 2010

    Japanese Society for Thermal Medicine

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