Revised Diagnostic Criteria for Stevens-Johnson syndrome (SJS) / toxic epidermal necrolysis (TEN)

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  • SUEKI Hirohiko
    Department of Dermatology, Showa University, School of Medicine

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  • Stevens-Johnson syndrome (SJS) / toxic epidermal necrolysis (TEN) の診断基準改訂
  • Stevens-Johnson syndrome(SJS)/toxic epidermal necrolysis(TEN)ノ シンダン キジュン カイテイ

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<p>　The current revision of the diagnostic criteria for SJS/TEN was developed in order to i) establish a method for excluding erythema multiforme (EM) major ; ii) provide detailed descriptions about the clinical findings of the disease, such as its skin manifestations and systemic symptoms ; and iii) increase the consistency of the international classification. The aim of this report was to reinforce the important role that dermatologists have during the diagnosis of SJS/TEN. Clinicians should differentiate between SJS and EM major based on a comprehensive assessment of five essential criteria, including malaise, the response to treatment, and the degree of epidermal necrosis according to histological examinations. Detailed cutaneous, histological, and systemic findings have been added to the revised criteria. Diagnoses of SJS/TEN should be made based on the fulfillment of all essential criteria throughout the course of the patient's disease while also considering supporting findings.</p>

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