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Improvement of Cancer Cachexia with Chemothermotherapy in a Patient with Advanced Pancreatic Cancer
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- TAKARA MINORU
- Department of Urology, Matsuyama West Hospital
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- AKAO JUMPEI
- Department of Urology, Matsuyama West Hospital
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- NAITO TAKEO
- Internal Medicine, Matsuyama West Hospital
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- KOHNO TSUNEFUMI
- Internal Medicine, Matsuyama West Hospital
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- HIRATA HIROSHI
- Department of Urology, Yamaguchi University School of Medicine
Bibliographic Information
- Other Title
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- 温熱化学療法が有効であった癌悪液質を伴った末期膵癌の一例
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Description
The ultimate goal of cancer treatment is to achieve a complete eradication of the cancer. However, patients with terminal cancer are also treated to obtain an improvement in their quality of life (QOL).<BR> In this report, we describe the dramatic response of an end-stage pancreatic cancer patient with cachexia to a combination of hyperthermia (HT) and chemotherapy (CH). The patient was treated with a combination of intermittent 5-FU/cisplatin (CDDP) therapy and HT. Three months later, the local recurrent cancer had disappeared, the liver metastases were reduced by 80%, the lung metastatic lesion was markedly reduced, tumor markers had returned to normal, and the cachexia had been almost reversed. Performance status (PS) improved from 4 to 1, QOL improved, and the patient survived until his 258th hospital day.<BR> In this patient, the combination of CH and HT was useful not only for improvement of cachexia, but also for tumor reduction. A possible mechanism leading to this effect is discussed.
Journal
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- Thermal Medicine
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Thermal Medicine 23 (4), 159-170, 2007
Japanese Society for Thermal Medicine
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Details 詳細情報について
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- CRID
- 1390282680263366144
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- NII Article ID
- 10029677158
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- NII Book ID
- AN10084762
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- ISSN
- 18823750
- 18822576
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- NDL BIB ID
- 9330891
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL Search
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed