Safety evaluation of Grifola gargal, an edible basidiomycete from Chile

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  • チリ産食用担子菌Grifola gargalの安全性評価

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Abstract

The purpose of this study was to evaluate the safety of Grifola gargal fruit body. Items for the safety assessment test were toxicity and mutagenicity. In 30-day and 100-day subchronic toxicity studies of G. gargal fruit body dry powder (GFD), all animals gained weight No changes attributable to GFD treatment in these subchronic toxicity studies were observed in overall condition or hematological parameters. No adverse effects or mortality were observed during these toxicity test periods. Additionally, the mutagenicity of the extracts from GFD was evaluated by a preincubation method using a modified Ames test. There was no mutagenicity of GFD extract (up to 5,000μg/plate) towards the two tested strains (TA98 and TA100), with or without metabolic activation (S9). These findings suggest that the fruit body of G. gargal was not toxic under these measurement conditions.

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