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- 成松 久
- 産業技術総合研究所 糖鎖医工学研究センター
書誌事項
- タイトル別名
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- Development of basic tools for glycoscience and their application to cancer diagnosis
- トウサ ケンキュウ ノ タメ ノ キバン ツール カイハツ オヨビ ソノ オウヨウ ト ジツヨウカ : カコ 10ネンカン ノ サン ソウケン トウサイ コウガク ケンキュウ センター ノ ケンキュウ センリャク
- — A 10-year strategy of the Research Center for Medical Glycoscience of AIST —
- － 過去10年間の産総研糖鎖医工学研究センターの研究戦略 －
この論文をさがす
説明
We proposed a 10-year strategy for the development of a new scientific field, glycoscience. Initially, we developed basic technological tools to help scientists and engineers enter this field. As the first project, we exhaustively discovered glycogenes and carried out their functional analyses. The fruits of this work led to several follow-on projects: 1) technology for enzyme synthesis of glycans, 2) technology for structural analysis of glycans, and 3) analysis of biological functions of glycans. The basic tools, developed in the first 5 years of our 10-year strategy, were applied to the development of more useful products, e.g., development of disease biomarkers, particularly for cancer diagnosis. We are also close to achieving the practical use of a liver fibrosis marker and a cholangiocarcinoma marker for diagnosis. Moreover, we are pursuing development of biomarkers for diagnosis of other cancers. The successful research results for these 10 years have now been transferred to the world, in particular, Asian countries, and have resulted in collaborative research contracts with domestic and overseas research groups.
収録刊行物
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- Synthesiology
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Synthesiology 5 (3), 190-203, 2012
国立研究開発法人 産業技術総合研究所
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詳細情報 詳細情報について
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- CRID
- 1390282680271878784
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- NII論文ID
- 130004952732
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- NII書誌ID
- AA12294844
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- COI
- 1:CAS:528:DC%2BC38XhtlGqtrzL
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- ISSN
- 18827365
- 18826229
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- NDL書誌ID
- 023931212
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可
