金属錯体反応制御を目指した蛋白質分子設計

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タイトル別名
  • Design of Protein Scaffolds for Chemical Reactions Catalyzed by Metal Complexes and Nanoparticles
  • キンゾク サクタイ ハンノウ セイギョ オ メザシタ タンパクシツ ブンシ セッケイ

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In recent years, efforts to design protein monomers and assemblies conjugated with metal complexes have attracted much attention in the field of coordination chemistry because protein scaffolds provide precise coordination spaces. While several researchers have reported modifications in spherical- and tube-like proteins with metal complexes, it is still difficult to control the coordination properties of the metal complexes attached to the proteins. The author has succeeded in the functionalization of protein scaffolds, such as myoglobin, ferritin, and component proteins isolated from bacteriophage T4, by precise conjugations of various metal complexes. This account describes my recent research studies involving preparation of metal complexes/protein composites, their crystal structures, and the molecular design of bio-inspired systems encompassing catalysts, electrochemistry, and inorganic materials using the protein scaffolds.

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