Novel Syntheses of Carbapenams Using Transition Metals

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  • Mori Miwako
    Graduate School of Pharmaceutical Sciences, Hokkaido University
  • Kozawa Yuji
    Graduate School of Pharmaceutical Sciences, Hokkaido University
  • Takimoto Masanori
    Graduate School of Pharmaceutical Sciences, Hokkaido University

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Carbapenams, which are important β-lactam antibiotics and have highly strained 4-5 fused-membered ring systems, could be synthesized using ruthenium- or palladium-catalyzed cyclization.

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