書誌事項
- タイトル別名
-
- Stereocontrol between Remote Atom Centers Using Chiral Acetals and its Application to Asymmetric Syntheses of Natural Products
- コウガク カッセイ アセタールルイ オ リヨウ スル エンカクイ フセイ ユウドウ ハンノウ ノ カイハツ ト テンネンブツ フセイ ゴウセイ エ ノ オウヨウ
この論文をさがす
抄録
Intramolecular haloetherification of the ene acetals prepared from chiral non-racemic C2-symmetric diols and achiral 4-pentenal or 5-heptenal proceeded in diastereoselective manners to form two asymmetric centers. The reaction was applied to synthesize optically active 1,4- and 1,5-diols. On the other hand, intramolecular haloetherification of diene acetals proceeded in two different manners. The intramolecular haloetherification of the diene acetals, prepared from chiral hydrobenzoin and σ-symmetric cyclohexa-1,4-dienes, proceeded with one olefin in a diastereoselective manners and gave the compounds having one remained olefin. However, the reaction of the acyclic diene acetals, prepared from hydrobenzoin and σ-symmetric 1,7-dienes, occurred novel double haloetherification giving four newly formed chiral stereocenters. The developed reactions were applied to synthesize optically active natural products, a civet constituent, scyphostatin, (+)-Sch 642305, rublenolide and rubrynolide.
収録刊行物
-
- 有機合成化学協会誌
-
有機合成化学協会誌 67 (6), 606-617, 2009
公益社団法人 有機合成化学協会
- Tweet
キーワード
詳細情報 詳細情報について
-
- CRID
- 1390282680287896192
-
- NII論文ID
- 10024969346
-
- NII書誌ID
- AN0024521X
-
- COI
- 1:CAS:528:DC%2BD1MXntlOmtbY%3D
-
- ISSN
- 18836526
- 00379980
-
- NDL書誌ID
- 10334752
-
- 本文言語コード
- ja
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可