-
- SASAKI Tadashi
- The Faculty of Pharmacy, Tokyo Science Univ.
-
- KANEMATSU Ken
- The Faculty of Pharmacy, Tokyo Science Univ.
-
- SAKAKIBARA Masako
- The Faculty of Pharmacy, Tokyo Science Univ.
Bibliographic Information
- Other Title
-
- 含硫アミノ酸のジクロルアセチル化
- ガンリュウアミノサン ノ ジクロルアセチルカ
Search this article
Abstract
Cancer inhibitors may be mentioned as one of the most urgently needed chemicals at present. It was found that a certain amino acid showed carcinogenic inhibition. In this report, the synthesis of sulfur-containing amino acids, especially of dichloroacetyl derivatives are described. Methionine, its oxidized substances and its esters, cysteine, cystine and its esters were selected as starting materials. Their acylations were made by (A) Schotetn-Baumann's method and (B) by Kameda's method. The results indicated that the sulfur-containing amino acids in general gave higher yield and higher purity of objective compounds in the B method than in the A method, while the synthesis was easier by use of the A Method in case of esters.
Journal
-
- Journal of Synthetic Organic Chemistry, Japan
-
Journal of Synthetic Organic Chemistry, Japan 22 (8), 654-656, 1964
The Society of Synthetic Organic Chemistry, Japan
- Tweet
Keywords
Details 詳細情報について
-
- CRID
- 1390282680288264960
-
- NII Article ID
- 130000928954
-
- NII Book ID
- AN0024521X
-
- ISSN
- 18836526
- 00379980
-
- NDL BIB ID
- 9213825
-
- Data Source
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- Abstract License Flag
- Disallowed