MALEBREAST CANCER

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Other Title
  • 男性乳癌
  • CLINOCOPATHOLOGICAL FEATURES AND TIME TRENDS
  • 臨床像と経時的変遷

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Thirty-nine cases (40 lesions) of carcinoma of the male breast dealt by us from 1946 through December 1994 were reviewed clinicopathologically to elucidate the clinical features of the disease and to analyze epidemiologically the time trend for this malignancy of rare occurrence. The results thus yielded may be briefly summarized as follows: The number of early stage cases increased as diagnostic capabilities improved and as knowledge of the disease popularized with the years. Modified radical mastectomy has become a principal surgical approach as in female breast cancer cases. However, disease-free survival and survival rates remained virtually unchanged. As regards to clinical features of this malignancy, its incidence was low (accounting for 0.34% of all breast cancers) and occurred mostly in advanced age (mean age at onset: 63.4 yrs). The location of tumors was in the vicinity of the mammary papilla and the disease was found in an early stage in most cases. Histologically, papillo-tubular carcinoma and solid-tubular carcinoma were more frequent than scirrhous carcinoma. The proportion of cases negative for histologically proven metastatic involvement of regional lymph nodes was high and, moreover, the positive rate of hormone receptors was exceedingly high, a fact suggesting the usefulness of endocrine therapy. The prognosis did not seem to be poor on the whole and was rather favorable compared to that of females, setting limitis to statistics after 1981.<br> Male patients of old age presenting mammary symptoms such as palpable mass in the breast and nipple discharge should be examined carefully for evidence of breast cancer which is by no means an unlikely possibility.

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