MULTIPLE LYMPHOMATOUS POLYPOSIS OF THE GASTROINTESTINAL TRACT-REPORT OF A CASE-

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  • 消化管multiple lymphomatous polyposisの1例

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Abstract

A 70-year-old man was admitted to the hospital on April 23, 1985 because of umbilical pain and an ileocecal tumor. An X-ray examintion on admission revealed multiple polypoid lesions in the entire large intestine. On endoscopic examination, numerous polypoid lesions, rainging from 5-6 mm in diameter were seen in the large intestine. Pathological examination of biopsy specimen showed no malignant finding. Multiple lymphomatous polyposis was suspected, and the patient was operated on June 10, 1985. Examination of the fresh resected specimen revealed that the lesions were densely distributed in the ascending colon and ileum. Examination of the cut specimen showed that the cellular prolifiration was limited to mucosal and submucosal layers. The cell was diagnosed as malignant lymphoma composed of small B cells. These findings confirmed the diagnosis of multiple lymphomatous polyposis of the gastrointestinal tract, which was first proposed by Cornes in 1961. The differential diagnoses of multiple lymphomatous polyposis includes adenomatous polyps, with or without carcinomatous degeneration, familial polyposis and syndromes of Peutz-Jeghers and nodular lymphoid hyperplasia with hypogammaglobulinemia.

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