薬剤耐性伝達因子R因子をもつ菌に特異なr+抗原について

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doi:10.2974/kmj1951.16.322

1. An antibody, specifically reacting with R⁺ strains, was demonstrated in an immune serum obtained by injecting a rabbit either with R⁺_100-1 strain of E.coli or with R⁺ strain of Salmonella 2. E. coli r⁺ antiserum and S r⁺ antiserum were absorbed with E.coli R⁺ strain and Salmonella R⁺ strain, alternately. Thc result indicated that r⁺ antigens of E.coli and Salmonella wonld have their specific antigenicities as well as common antigenicity. 3. Bacterial suspensions of E.coli R⁺ and Salmonella R⁺ strain were treated with a blendor, and the whole was centrifuged. Then the supernatant was recentrifuged twice. first at 18, 000 r. p. m.and then at 38, 000 r.p.m. And r⁺ antigenicity was demonstrated in the fraction which was sedimented by the 38, 000 r p.m.centrifugation. 4. The r⁺ antigenicity of the living cells or of its ultracentrifuged fraction was lost when it was heated at 100°C for 30 min., or treated with proteinases such as trypsin, ficin or bromelin. It is consequently assumed that the r⁺ antigen would have proteinic properties.

薬剤耐性伝達因子R因子をもつ菌に特異なr<SUP>+</SUP>抗原について

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