Effect of Protein Quality on the Changes of Free Amino Acids in Plasma, Liver, and Muscle of Rats Recovering from Protein Deficiency

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  • MIYAOKA Yoko
    Department of Food Science and Nutrition, Nara Women's University,
  • MIZUKAMI Taiko
    Department of Food Science and Nutrition, Nara Women's University,
  • HORIKAWA Ranko
    Department of Food Science and Nutrition, Nara Women's University,

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Other Title
  • 白ネズミにおけるたん白欠乏からの回復期における血漿・肝臓・筋肉中の遊離アミノ酸濃度の変化に及ぼすたん白質の影響
  • ハク ネズミ ニ オケル タンパク ケツボウ カラ ノ カイフクキ ニ オケル

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Description

Changes in the concentration of free amino acids were studied in plasma, liver, and muscle of rats recovering from protein deficiency in order to investigate the relationship of plasma amino acid level to the amino acid pool of liver and muscle.<BR>Protein-depleted rats were fed three diets of different protein quality (10% casein, 10% albumin, and 20% gluten) for 1, 2, 3, 5, 7, and 14 days, respectively. Concentration ratios of free amino acids in liver and muscle to those in plasma were calculated for each group. The ratios between the liver and plasma free essential amino acids did not change significantly during the depletion period, but resulted in characteristic changes during the recovery period depending upon which diet was fed. The ratios of branched amino acids elevated sharply up to the third day of recovery and decreased thereafter in the casein and albumin groups, while they gradually increased up to the 14th day of recovery in the gluten group. The changes in concentration ratios between the lier and plasma amino acids were similar to those in the protein to DNA ratio of the liver, and the decrease in the ratios during the recovery period of the 3rd-14th day could be accounted for by the amino acid requirement of rat.<BR>On the other hand, the ratios of the essential amino acids between muscle and plasma hardly changed during the perod of both protein depletion and recovery. The ratios of the non-essential amino acids, however, decreased in depletion and returned to normal values by the third day of recovery to stay there during the remaining period. This pattern of change in the non-essential amino acids was similar to that of change in the protein to DNA ratio in muscle.

Journal

  • Eiyo To Shokuryo

    Eiyo To Shokuryo 33 (5), 317-325, 1980

    JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE

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